Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSH | P09668 | 1/20 | 0.43 |
| ▸ | SPPL2A | Q8TCT8 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8490546 | 1.00 | HTT (0.47) | HTTKLK5TSHRNPC1RAB9A | |
| SCHEMBL27527710 | 0.87 | KLK5 (0.51) | KLK5NPC1RAB9ATRPM8BCHE | |
| SCHEMBL7462812 | 0.87 | KLK5 (0.51) | KLK5NPC1RAB9ATRPM8BCHE | |
| SCHEMBL7492515 | 0.87 | KLK5 (0.51) | KLK5NPC1RAB9ATRPM8BCHE | |
| SCHEMBL7458154 | 0.87 | KLK5 (0.51) | KLK5NPC1RAB9ATRPM8BCHE | |
| SCHEMBL7492033 | 0.87 | KLK5 (0.51) | KLK5NPC1RAB9ATRPM8BCHE | |
| SCHEMBL8486300 | 0.86 | TSHR (0.49) | HTTKLK5TSHRNPC1RAB9A | |
| SCHEMBL7298922 | 0.84 | CA2 (0.47) | HTTKLK5TSHRNPC1RAB9A | |
| SCHEMBL5650179 | 0.84 | KLK5 (0.48) | KLK5TRPM8CTSLCTSBSPPL2A | |
| SCHEMBL638912 | 0.83 | KLK5 (0.65) | KLK5CTSKCTSLCTSBPSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5936104-A | Process for producing 1,2-epoxy-3-amino-4-phenylbutane derivatives | KANEKA CORPORATION (JP) | 1999-08-10 | — | — | US | disclosed |