Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.34 |
| ▸ | EED | O75530 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | CCR3 | P51677 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8491954 | 0.88 | LMNA (0.36) | LMNATSHRBCAT2EEDHRH1 | |
| SCHEMBL8607785 | 0.87 | LMNA (0.37) | LMNABCAT2EEDHRH1CCR3 | |
| SCHEMBL8491655 | 0.85 | TSHR (0.37) | LMNATSHRBCAT2EEDHRH1 | |
| SCHEMBL8491543 | 0.83 | TSHR (0.35) | LMNATSHRBCAT2EEDHRH1 | |
| SCHEMBL8495604 | 0.76 | POLB (0.36) | LMNABCAT2EEDHRH1CCR3 | |
| SCHEMBL8489172 | 0.75 | TSHR (0.37) | LMNATSHRBCAT2EEDKDM4E | |
| SCHEMBL8684225 | 0.73 | TSHR (0.33) | LMNATSHRBCAT2EEDCNR2 | |
| SCHEMBL8608675 | 0.72 | LMNA (0.38) | LMNABCAT2EEDHRH1CCR3 | |
| SCHEMBL8762938 | 0.71 | LMNA (0.38) | LMNATSHRBCAT2EEDSLC9A1 | |
| SCHEMBL8491927 | 0.69 | TSHR (0.34) | TSHRCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859283-A | TERTIARY-BUTYL 3-CYCLOALKYL-3-OXOPROPIONATE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-12 | — | — | US | disclosed |
| US-5747424-A | HEATING AN AROMATIC DIKETONE WITH A SALT OF HYDROXYLAMINE IN A SOLVENT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-05-05 | — | — | US | disclosed |