Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PRCP | P42785 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3464616 | 0.76 | AKR1C1 (0.42) | OPRM1SMN1; SMN2OPRK1OPRL1ALDH1A1 | |
| SCHEMBL8492019 | 0.75 | OPRM1 (0.37) | OPRM1SMN1; SMN2PRCPSIGMAR1OPRD1 | |
| SCHEMBL7450867 | 0.72 | AKR1C1 (0.47) | SMN1; SMN2PRCPSIGMAR1SLC6A4KCNH2 | |
| SCHEMBL6931655 | 0.70 | AKR1C1 (0.45) | OPRM1PRCPSIGMAR1OPRD1SLC6A4 | |
| SCHEMBL324341 | 0.68 | MEN1 (0.41) | OPRM1OPRK1OPRL1 | |
| SCHEMBL10603880 | 0.68 | OPRM1 (0.59) | OPRM1SMN1; SMN2OPRD1OPRK1SLC22A1 | |
| SCHEMBL4024768 | 0.63 | — | — | |
| SCHEMBL15043695 | 0.63 | OPRM1 (0.58) | OPRM1OPRD1OPRK1SLC6A4OPRL1 | |
| SCHEMBL6137902 | 0.62 | SLC6A2 (0.50) | SMN1; SMN2SLC6A4ALDH1A1TSHR | |
| SCHEMBL23225663 | 0.62 | OPRM1 (0.75) | OPRM1PRCPSIGMAR1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999031077-A1 | ARYLPIPERAZINES HAVING ACTIVITY AT THE SEROTONIN 1A RECEPTOR | ELI LILLY AND COMPANY (US) | 1999-06-24 | — | — | WO | disclosed |