Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8491501 | 1.00 | HTT (0.37) | HTTGAASMN1; SMN2TSHRNPSR1 | |
| SCHEMBL8489094 | 0.86 | ALDH1A1 (0.34) | HTTSMN1; SMN2TSHRNPSR1MAPT | |
| SCHEMBL8489098 | 0.86 | ALDH1A1 (0.34) | HTTSMN1; SMN2TSHRNPSR1MAPT | |
| SCHEMBL8491832 | 0.85 | KMT2A (0.39) | SMN1; SMN2TSHRMAPTKMT2AALDH1A1 | |
| SCHEMBL8491834 | 0.85 | KMT2A (0.39) | SMN1; SMN2TSHRMAPTKMT2AALDH1A1 | |
| SCHEMBL8673741 | 0.84 | CACNA1B (0.40) | SMN1; SMN2NPSR1TYK2 | |
| SCHEMBL8673739 | 0.84 | CACNA1B (0.40) | SMN1; SMN2NPSR1TYK2 | |
| SCHEMBL7552516 | 0.83 | TYK2 (0.38) | HTTGAATSHRTYK2MAPT | |
| SCHEMBL7552513 | 0.83 | TYK2 (0.38) | HTTGAATSHRTYK2MAPT | |
| SCHEMBL8489165 | 0.83 | MEN1 (0.38) | GAANPSR1MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859283-A | TERTIARY-BUTYL 3-CYCLOALKYL-3-OXOPROPIONATE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-12 | — | — | US | disclosed |
| US-5747424-A | HEATING AN AROMATIC DIKETONE WITH A SALT OF HYDROXYLAMINE IN A SOLVENT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-05-05 | — | — | US | disclosed |
| US-5656573-A | Herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-12 | — | — | US | disclosed |
| US-5650533-A | Intermediates to herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-07-22 | — | — | US | disclosed |
| EP-0527036-B1 | 4-Benzoylisoxazole derivatives and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1996-11-06 | — | — | EP | disclosed |
| EP-0527036-A1 | 4-Benzoylisoxazole derivatives and their use as herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1993-02-10 | — | — | EP | disclosed |