Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | PRKCA | P17252 | 4/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8495859 | 0.96 | KDM4E (0.42) | KDM4ENPC1RAB9AHSD17B10PPARG | |
| SCHEMBL8495846 | 0.93 | PPARG (0.40) | KDM4ENPC1RAB9AHSD17B10PPARG | |
| SCHEMBL8494039 | 0.93 | PPARG (0.40) | KDM4ENPC1RAB9AHSD17B10PPARG | |
| SCHEMBL8490807 | 0.91 | KDM4E (0.47) | KDM4ENPC1RAB9AHSD17B10PPARG | |
| SCHEMBL8497286 | 0.91 | PPARG (0.40) | KDM4ENPC1RAB9AHSD17B10PPARG | |
| SCHEMBL8494895 | 0.91 | PPARG (0.40) | KDM4ENPC1RAB9AHSD17B10PPARG | |
| SCHEMBL8493760 | 0.90 | KDM4E (0.46) | KDM4ENPC1RAB9AHSD17B10PPARG | |
| SCHEMBL8494105 | 0.90 | CYP2A6 (0.40) | ALOX5 | |
| SCHEMBL8493352 | 0.90 | ALOX5 (0.39) | ALOX5 | |
| SCHEMBL8496251 | 0.88 | ALOX5 (0.44) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0598117-B1 | BENZOPYRAN DERIVATIVE AND ANTIALLERGIC AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT | DAINIPPON INK & CHEMICALS (JP) | 1999-06-30 | — | — | EP | disclosed |
| US-5428059-A | Benzopyran derivatives and an anti-allergic agent possessing the same as the active ingredient | DAINIPPON INK & CHEMICALS, INC. (JP) | 1995-06-27 | — | — | US | disclosed |
| EP-0598117-A1 | BENZOPYRAN DERIVATIVE AND ANTIALLERGIC AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1994-05-25 | — | — | EP | disclosed |