SCHEMBL8495010

SCHEMBL8495010

Cc1nc([CH]C2CCC2)c[nH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5345993 0.66
SCHEMBL13804377 0.64
SCHEMBL9728320 0.64
SCHEMBL8495012 0.63 CYP11B2 (0.36)
SCHEMBL3391231 0.62 HRH4 (0.37)
SCHEMBL16995220 0.61
SCHEMBL65108 0.58
SCHEMBL6247431 0.57 SMN1; SMN2 (0.33)
SCHEMBL21193094 0.56 CHRM2 (0.43)
Hydrochloric Acid SCHEMBL7285171 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999051598-A1 SUBSTITUTED 9H-PYRIDINO[2,3-b]INDOLE AND 9H-PYRIMIDINO[4,5-b]INDOLE DERIVATIVES: SELECTIVE NEUROPEPTIDE y RECEPTOR LIGANDS NEUROGEN CORPORATION (US) 1999-10-14 WO claimed