Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.84 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.84 |
| ▸ | MEN1 | O00255 | 5/20 | 0.84 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.84 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.84 |
| ▸ | RECQL | P46063 | 2/20 | 0.84 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.84 |
| ▸ | MAPT | P10636 | 7/20 | 0.76 |
| ▸ | TP53 | P04637 | 4/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.72 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.72 |
| ▸ | ESR1 | P03372 | 6/20 | 0.71 |
| ▸ | PGR | P06401 | 3/20 | 0.71 |
| ▸ | AR | P10275 | 3/20 | 0.71 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.71 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.71 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL147037 | 0.92 | LMNA (1.00) | LMNACYP3A4KMT2AMEN1ALOX15 | |
| SCHEMBL7260222 | 0.92 | LMNA (1.00) | LMNACYP3A4KMT2AMEN1ALOX15 | |
| SCHEMBL12072310 | 0.92 | LMNA (1.00) | LMNACYP3A4KMT2AMEN1ALOX15 | |
| SCHEMBL8643294 | 0.92 | LMNA (1.00) | LMNACYP3A4KMT2AMEN1ALOX15 | |
| SCHEMBL12186917 | 0.92 | LMNA (1.00) | LMNACYP3A4KMT2AMEN1ALOX15 | |
| SCHEMBL8991456 | 0.92 | LMNA (1.00) | LMNACYP3A4KMT2AMEN1ALOX15 | |
| SCHEMBL13177178 | 0.92 | LMNA (1.00) | LMNACYP3A4KMT2AMEN1ALOX15 | |
| SCHEMBL24103244 | 0.89 | LMNA (0.84) | LMNACYP3A4KMT2AMEN1ALOX15 | |
| SCHEMBL9273487 | 0.88 | LMNA (0.82) | LMNACYP3A4KMT2AMEN1ALOX15 | |
| SCHEMBL27900238 | 0.88 | LMNA (0.82) | LMNACYP3A4KMT2AMEN1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736103-A4 | NUCLEOTIDE-DIRECTED ASSEMBLY OF BIMOLECULAR AND MULTIMOLECULAR DRUGS AND DEVICES | CUBICCIOTTI ROGER S (US) | 1999-07-28 | — | — | EP | disclosed |
| EP-0736103-A1 | NUCLEOTIDE-DIRECTED ASSEMBLY OF BIMOLECULAR AND MULTIMOLECULAR DRUGS AND DEVICES | Cubicciotti, Roger S. (US) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995016788-A1 | NUCLEOTIDE-DIRECTED ASSEMBLY OF BIMOLECULAR AND MULTIMOLECULAR DRUGS AND DEVICES | CUBICCIOTTI ROGER S (US) | 1995-06-22 | — | — | WO | disclosed |