Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNNC1 | P63316 | 5/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.50 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.50 |
| ▸ | GPR183 | P32249 | 1/20 | 0.50 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.50 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | TACR2 | P21452 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SHBG | P04278 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL903515 | 0.79 | S1PR1 (0.61) | TNNC1S1PR1S1PR4S1PR3SGPL1 | |
| SCHEMBL2726354 | 0.77 | S1PR1 (0.51) | TNNC1S1PR1S1PR4S1PR3SGPL1 | |
| SCHEMBL8495721 | 0.76 | S1PR1 (0.66) | TNNC1S1PR1S1PR4S1PR3SGPL1 | |
| SCHEMBL26881637 | 0.76 | S1PR1 (0.66) | TNNC1S1PR1S1PR4S1PR3SGPL1 | |
| SCHEMBL8500217 | 0.76 | S1PR1 (0.66) | TNNC1S1PR1S1PR4S1PR3SGPL1 | |
| SCHEMBL8498533 | 0.76 | S1PR1 (0.66) | TNNC1S1PR1S1PR4S1PR3SGPL1 | |
| SCHEMBL8498597 | 0.76 | S1PR1 (0.66) | TNNC1S1PR1S1PR4S1PR3SGPL1 | |
| Hydrochloric Acid SCHEMBL25371925 | 0.75 | S1PR1 (0.67) | TNNC1S1PR1S1PR4S1PR3SGPL1 | |
| SCHEMBL10036574 | 0.75 | S1PR1 (0.56) | TNNC1S1PR1S1PR4S1PR3SGPL1 | |
| SCHEMBL27997928 | 0.75 | TNNC1 (0.46) | TNNC1S1PR1S1PR4S1PR3SGPL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952316-A | FOR TREATING AUTOIMMUNE DISEASES, E.G., RHEUMATIOD ARTHRITIS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-09-14 | — | — | US | disclosed |
| EP-0627406-B1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5719176-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-02-17 | — | — | US | disclosed |
| US-5604229-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-02-18 | — | — | US | disclosed |
| EP-0627406-A1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-12-07 | — | — | EP | disclosed |