Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 9/20 | 0.46 |
| ▸ | CNR2 | P34972 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | USP10 | Q14694 | 1/20 | 0.41 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.41 |
| ▸ | USP13 | Q92995 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8517042 | 0.92 | MEN1 (0.49) | CNR1CNR2MEN1KMT2AEGFR | |
| SCHEMBL8506836 | 0.88 | GALR3 (0.44) | CNR1CNR2MEN1KMT2AEGFR | |
| SCHEMBL8516559 | 0.84 | GALR3 (0.45) | MEN1KMT2AEGFRCYP1A2CYP2D6 | |
| SCHEMBL9609147 | 0.84 | MEN1 (0.41) | MEN1KMT2AUSP10PIK3C3USP13 | |
| SCHEMBL8516740 | 0.82 | CNR1 (0.36) | CNR1CNR2EGFRLMNAHTT | |
| SCHEMBL9608200 | 0.82 | CNR1 (0.43) | CNR1CNR2MEN1KMT2AUSP10 | |
| SCHEMBL8507035 | 0.81 | LPAR2 (0.51) | CNR1CNR2 | |
| SCHEMBL8491976 | 0.81 | LPAR1 (0.45) | CNR1CNR2 | |
| SCHEMBL8497510 | 0.81 | CNR1 (0.37) | CNR1CNR2MEN1KMT2AEGFR | |
| SCHEMBL12960923 | 0.80 | MEN1 (0.38) | MEN1KMT2AEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2455371-A1 | 4-(3-BUTYNYL)AMINOPYRIMIDINE DERIVATIVES AS PEST CONTROL AGENTS FOR AGRICULTURAL AND HORTICULTURAL USE | SDS Biotech K. K. (JP) | 2012-05-23 | — | — | EP | disclosed |