Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 5/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PDE1A | P54750 | 2/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | PDE8B | O95263 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.33 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9609147 | 0.94 | MEN1 (0.41) | MEN1KMT2APDE1BLPAR2EGFR | |
| SCHEMBL8517042 | 0.89 | MEN1 (0.49) | MEN1KMT2APDE1BLPAR2EGFR | |
| SCHEMBL9609149 | 0.87 | GALR3 (0.45) | MEN1KMT2AIRAK4EGFR | |
| SCHEMBL8516559 | 0.85 | GALR3 (0.45) | MEN1KMT2AEGFR | |
| SCHEMBL12960927 | 0.84 | MEN1 (0.44) | MEN1KMT2APDE1BEGFRTP53 | |
| SCHEMBL8497996 | 0.80 | CNR1 (0.46) | MEN1KMT2AEGFR | |
| SCHEMBL8490934 | 0.77 | RAB9A (0.46) | MEN1KMT2AIRAK4EGFR | |
| SCHEMBL8491653 | 0.77 | EGFR (0.49) | MEN1KMT2AIRAK4LPAR2EGFR | |
| SCHEMBL8506836 | 0.76 | GALR3 (0.44) | MEN1KMT2ALPAR2EGFR | |
| SCHEMBL8484019 | 0.76 | GALR3 (0.47) | MEN1KMT2AIRAK4EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011007839-A1 | 4-(3-BUTYNYL)AMINOPYRIMIDINE DERIVATIVES AS PEST CONTROL AGENTS FOR AGRICULTURAL AND HORTICULTURAL USE | 株式会社エス・ディー・エス バイオテック (JP) | 2011-01-20 | — | — | WO | disclosed |