Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8497448 | 1.00 | CA2 (0.53) | CA2TAAR1CYP4F2CYP4A11GAA | |
| SCHEMBL1045947 | 1.00 | CA2 (0.53) | CA2TAAR1CYP4F2CYP4A11GAA | |
| SCHEMBL8499024 | 1.00 | CA2 (0.53) | CA2TAAR1CYP4F2CYP4A11GAA | |
| SCHEMBL8498567 | 1.00 | CA2 (0.53) | CA2TAAR1CYP4F2CYP4A11GAA | |
| SCHEMBL8499782 | 1.00 | CA2 (0.53) | CA2TAAR1CYP4F2CYP4A11GAA | |
| SCHEMBL8498688 | 1.00 | CA2 (0.53) | CA2TAAR1CYP4F2CYP4A11GAA | |
| SCHEMBL8495744 | 1.00 | CA2 (0.53) | CA2TAAR1CYP4F2CYP4A11GAA | |
| SCHEMBL1047918 | 1.00 | CA2 (0.53) | CA2TAAR1CYP4F2CYP4A11GAA | |
| SCHEMBL8497303 | 1.00 | CA2 (0.53) | CA2TAAR1CYP4F2CYP4A11GAA | |
| SCHEMBL1287204 | 0.98 | CA2 (0.52) | CA2TAAR1CYP4F2CYP4A11GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952316-A | FOR TREATING AUTOIMMUNE DISEASES, E.G., RHEUMATIOD ARTHRITIS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-09-14 | — | — | US | disclosed |
| EP-0627406-B1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5719176-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-02-17 | — | — | US | disclosed |
| US-5604229-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-02-18 | — | — | US | disclosed |
| EP-0627406-A1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-12-07 | — | — | EP | disclosed |