Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8498360 | 1.00 | TSHR (0.45) | TSHRTP53EGLN1EGLN3HCAR2 | |
| SCHEMBL2546942 | 0.78 | CA2 (0.40) | TSHRALDH1A1CA2MAPK1SLC1A3 | |
| SCHEMBL6643504 | 0.78 | CA2 (0.40) | TSHRALDH1A1CA2MAPK1SLC1A3 | |
| SCHEMBL14285858 | 0.78 | USP2 (0.34) | TSHRCA2MAPK1SLC1A3SLC1A2 | |
| SCHEMBL811825 | 0.77 | USP2 (0.37) | TSHRCA2MAPK1SLC1A3SLC1A2 | |
| SCHEMBL811824 | 0.77 | USP2 (0.37) | TSHRCA2MAPK1SLC1A3SLC1A2 | |
| Maleic Acid SCHEMBL29895971 | 0.76 | TSHR (0.53) | TSHRTP53EGLN1EGLN3HCAR2 | |
| Fumaric Acid SCHEMBL28847621 | 0.76 | TSHR (0.53) | TSHRTP53EGLN1EGLN3HCAR2 | |
| Fumaric Acid SCHEMBL769454 | 0.76 | TSHR (0.53) | TSHRTP53EGLN1EGLN3HCAR2 | |
| SCHEMBL26575537 | 0.75 | HDAC1 (0.50) | TSHRCA2MAPK1SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0701991-B1 | Process for the preparation of lignin analogues and starting materials therefor | SHIONOGI & CO (JP) | 1999-01-20 | — | — | EP | disclosed |
| EP-0597107-B1 | LIGNAN ANALOG, PRODUCTION THEREOF, AND HYPOLIPIDEMIC DRUG | SHIONOGI & CO (JP) | 1996-07-03 | — | — | EP | disclosed |
| US-5502216-A | ANTICHOLESTEROL | SHIONOGI & CO., LTD. (JP) | 1996-03-26 | — | — | US | disclosed |
| EP-0701991-A1 | Process for the preparation of lignin analogues and starting materials therefor | SHIONOGI & CO., LTD. (JP) | 1996-03-20 | — | — | EP | disclosed |
| US-5449814-A | Dehydration; Michael condensation | SHIONOGI & CO., LTD. (JP) | 1995-09-12 | — | — | US | disclosed |
| US-5420333-A | Hydroxy ketone compounds | SHIONOGI & CO., LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0597107-A1 | LIGNAN ANALOG, PRODUCTION THEREOF, AND HYPOLIPIDEMIC DRUG | SHIONOGI & CO., LTD. (JP) | 1994-05-18 | — | — | EP | disclosed |