SCHEMBL849849

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16104653	0.93	PTH1R (0.46)	PTH1RMGLL
	SCHEMBL848993	0.92	PTH1R (0.52)	PTH1RMGLLSLC6A7ABL1
	SCHEMBL847650	0.92	PTH1R (0.59)	PTH1RMGLLHSD11B1SLC6A7ABL1
	SCHEMBL850512	0.90	PTH1R (0.51)	PTH1RMGLLSLC6A7
	SCHEMBL848537	0.90	PTH1R (0.50)	PTH1RMGLLSLC6A7ABL1
	SCHEMBL850080	0.90	PTH1R (0.50)	PTH1RMGLLSLC6A7GHSR
	SCHEMBL13552148	0.89	PTH1R (0.56)	PTH1RMGLL
	SCHEMBL849612	0.89	PTH1R (0.51)	PTH1RMGLLSLC6A7ABL1GHSR
	SCHEMBL847213	0.87	PTH1R (0.57)	PTH1RMGLL
	SCHEMBL849528	0.86	PTH1R (0.52)	PTH1RMGLLHSD11B1SLC6A7ABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.