Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25302330 | 0.80 | KCNJ1 (0.33) | KCNJ1GRM4 | |
| SCHEMBL13348654 | 0.80 | MEN1 (0.33) | KCNJ1 | |
| SCHEMBL18981723 | 0.79 | MEN1 (0.39) | KCNJ1 | |
| SCHEMBL28159727 | 0.78 | POLB (0.35) | KCNJ1GRM4 | |
| SCHEMBL27943884 | 0.78 | KCNJ1 (0.33) | KCNJ1 | |
| SCHEMBL24466695 | 0.76 | GRM4 (0.40) | GRM4 | |
| SCHEMBL19835245 | 0.76 | GRM4 (0.40) | GRM4 | |
| SCHEMBL28133243 | 0.71 | ALDH1A1 (0.43) | GRM4 | |
| SCHEMBL18648465 | 0.71 | GRM4 (0.37) | GRM4 | |
| SCHEMBL29953076 | 0.70 | MEN1 (0.36) | KCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018019765-A1 | HERBICIDAL PYRIMIDINE COMPOUNDS | BASF SE (DE) | 2018-02-01 | — | — | WO | disclosed |
| EP-0948497-A2 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND THEIR USE | Amgen inc. (US) | 1999-10-13 | — | — | EP | disclosed |
| WO-1998024782-A2 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND THEIR USE | AMGEN INC. (US) | 1998-06-11 | — | — | WO | disclosed |