Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAO1 | P09471 | 3/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.33 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.33 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8498953 | 1.00 | GNAO1 (0.40) | GNAO1HRH3ITGB3ITGA2BSLC6A4 | |
| SCHEMBL8500266 | 1.00 | GNAO1 (0.40) | GNAO1HRH3ITGB3ITGA2BSLC6A4 | |
| SCHEMBL8496786 | 1.00 | GNAO1 (0.40) | GNAO1HRH3ITGB3ITGA2BSLC6A4 | |
| SCHEMBL8499727 | 1.00 | GNAO1 (0.40) | GNAO1HRH3ITGB3ITGA2BSLC6A4 | |
| SCHEMBL8496358 | 1.00 | GNAO1 (0.40) | GNAO1HRH3ITGB3ITGA2BSLC6A4 | |
| SCHEMBL8496012 | 1.00 | GNAO1 (0.40) | GNAO1HRH3ITGB3ITGA2BSLC6A4 | |
| SCHEMBL8499546 | 1.00 | GNAO1 (0.40) | GNAO1HRH3ITGB3ITGA2BSLC6A4 | |
| SCHEMBL8499258 | 1.00 | GNAO1 (0.40) | GNAO1HRH3ITGB3ITGA2BSLC6A4 | |
| SCHEMBL8501707 | 1.00 | GNAO1 (0.40) | GNAO1HRH3ITGB3ITGA2BSLC6A4 | |
| SCHEMBL8499313 | 1.00 | GNAO1 (0.40) | GNAO1HRH3ITGB3ITGA2BSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952316-A | FOR TREATING AUTOIMMUNE DISEASES, E.G., RHEUMATIOD ARTHRITIS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-09-14 | — | — | US | disclosed |
| EP-0627406-B1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5719176-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-02-17 | — | — | US | disclosed |
| US-5604229-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-02-18 | — | — | US | disclosed |
| EP-0627406-A1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-12-07 | — | — | EP | disclosed |