Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 8/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8499485 | 0.87 | AR (0.58) | ARSRD5A2KCNH2 | |
| SCHEMBL8538276 | 0.86 | AR (0.56) | ARSRD5A2KCNH2 | |
| SCHEMBL8538278 | 0.86 | AR (0.56) | ARSRD5A2KCNH2 | |
| SCHEMBL8499903 | 0.85 | SRD5A1 (0.49) | SRD5A2 | |
| SCHEMBL8496146 | 0.81 | AR (0.61) | ARSRD5A2KCNH2 | |
| SCHEMBL8499041 | 0.80 | AR (0.61) | ARSRD5A2KCNH2 | |
| SCHEMBL8499758 | 0.79 | AR (0.51) | ARSRD5A2KCNH2 | |
| SCHEMBL8904438 | 0.79 | AR (0.57) | ARSRD5A2KCNH2 | |
| SCHEMBL8904439 | 0.79 | AR (0.57) | ARSRD5A2KCNH2 | |
| SCHEMBL8499496 | 0.77 | AR (0.60) | ARSRD5A2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649431-B1 | 17-AMINO SUBSTITUTED 4-AZASTEROID 5-ALPHA-REDUCTASE INHIBITORS | MERCK & CO INC (US) | 1999-08-11 | — | — | EP | claimed |