Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2090877 | 1.00 | L3MBTL1 (0.57) | L3MBTL1TDP1SIGMAR1IDO1KDM4E | |
| SCHEMBL8496478 | 1.00 | L3MBTL1 (0.57) | L3MBTL1TDP1SIGMAR1IDO1KDM4E | |
| SCHEMBL8499359 | 1.00 | L3MBTL1 (0.57) | L3MBTL1TDP1SIGMAR1IDO1KDM4E | |
| SCHEMBL791465 | 1.00 | L3MBTL1 (0.57) | L3MBTL1TDP1SIGMAR1IDO1KDM4E | |
| SCHEMBL8498124 | 1.00 | L3MBTL1 (0.57) | L3MBTL1TDP1SIGMAR1IDO1KDM4E | |
| SCHEMBL8500355 | 1.00 | L3MBTL1 (0.57) | L3MBTL1TDP1SIGMAR1IDO1KDM4E | |
| SCHEMBL8499737 | 1.00 | L3MBTL1 (0.57) | L3MBTL1TDP1SIGMAR1IDO1KDM4E | |
| SCHEMBL12982429 | 1.00 | L3MBTL1 (0.57) | L3MBTL1TDP1SIGMAR1IDO1KDM4E | |
| SCHEMBL8496079 | 1.00 | L3MBTL1 (0.57) | L3MBTL1TDP1SIGMAR1IDO1KDM4E | |
| SCHEMBL8499492 | 1.00 | L3MBTL1 (0.57) | L3MBTL1TDP1SIGMAR1IDO1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952316-A | FOR TREATING AUTOIMMUNE DISEASES, E.G., RHEUMATIOD ARTHRITIS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-09-14 | — | — | US | disclosed |
| EP-0627406-B1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5719176-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-02-17 | — | — | US | disclosed |
| US-5604229-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-02-18 | — | — | US | disclosed |
| EP-0627406-A1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-12-07 | — | — | EP | disclosed |