Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.66 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.66 |
| ▸ | S100A4 | P26447 | 2/20 | 0.53 |
| ▸ | PTPRC | P08575 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35211484 | 0.85 | MAPT (0.56) | MAPTRECQLKMT2AMCL1RXFP1 | |
| SCHEMBL166701 | 0.85 | MAPT (0.56) | MAPTRECQLKMT2AMCL1RXFP1 | |
| SCHEMBL4573599 | 0.81 | MAPT (0.53) | MAPTRECQLKMT2AMCL1RXFP1 | |
| SCHEMBL768880 | 0.81 | MAPT (0.53) | MAPTRECQLKMT2AMCL1RXFP1 | |
| SCHEMBL8062158 | 0.79 | MAPT (1.00) | MAPTRECQLKMT2AMCL1RXFP1 | |
| SCHEMBL30317814 | 0.79 | MAPT (1.00) | MAPTRECQLKMT2AMCL1RXFP1 | |
| SCHEMBL7248426 | 0.79 | MAPT (0.50) | MAPTRECQLKMT2AMCL1RXFP1 | |
| SCHEMBL16701465 | 0.79 | MAPT (0.50) | MAPTRECQLKMT2AMCL1RXFP1 | |
| SCHEMBL7253467 | 0.79 | MAPT (0.50) | MAPTRECQLKMT2AMCL1RXFP1 | |
| SCHEMBL1306345 | 0.78 | MAPT (0.49) | MAPTRECQLKMT2AMCL1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869693-A | Benzocyclobutenones and polymers derived therefrom | CARLETON UNIVERSITY (CA) | 1999-02-09 | — | — | US | disclosed |