Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.81 |
| ▸ | MAPT | P10636 | 2/20 | 0.81 |
| ▸ | MEN1 | O00255 | 1/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.81 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.81 |
| ▸ | HTT | P42858 | 1/20 | 0.72 |
| ▸ | PKM | P14618 | 2/20 | 0.69 |
| ▸ | THRB | P10828 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 3/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8499460 | 1.00 | ATM (0.81) | ATMMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL8498780 | 0.99 | ATM (0.83) | ATMMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL8498782 | 0.99 | ATM (0.83) | ATMMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL14733225 | 0.90 | MAPT (0.65) | ATMMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL8499239 | 0.90 | MAPT (1.00) | ATMMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL8498720 | 0.90 | MAPT (1.00) | ATMMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL8499578 | 0.90 | MAPT (1.00) | ATMMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL8498186 | 0.90 | MAPT (1.00) | ATMMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL8496580 | 0.90 | MAPT (1.00) | ATMMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL8499870 | 0.82 | PKM (0.79) | ATMMAPTMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952316-A | FOR TREATING AUTOIMMUNE DISEASES, E.G., RHEUMATIOD ARTHRITIS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-09-14 | — | — | US | disclosed |
| EP-0627406-B1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5719176-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-02-17 | — | — | US | disclosed |
| US-5604229-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-02-18 | — | — | US | disclosed |
| EP-0627406-A1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-12-07 | — | — | EP | disclosed |