Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.67 |
| ▸ | NAAA | Q02083 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL498601 | 1.00 | HRH1 (0.67) | HRH1NAAACYP1A2SMN1; SMN2CYP2C19 | |
| SCHEMBL2167965 | 1.00 | HRH1 (0.67) | HRH1NAAACYP1A2SMN1; SMN2CYP2C19 | |
| SCHEMBL2167104 | 1.00 | HRH1 (0.67) | HRH1NAAACYP1A2SMN1; SMN2CYP2C19 | |
| SCHEMBL7878429 | 1.00 | HRH1 (0.67) | HRH1NAAACYP1A2SMN1; SMN2CYP2C19 | |
| SCHEMBL16288588 | 1.00 | HRH1 (0.67) | HRH1NAAACYP1A2SMN1; SMN2CYP2C19 | |
| SCHEMBL498506 | 0.98 | HRH1 (0.63) | HRH1NAAACYP1A2SMN1; SMN2CYP2C19 | |
| SCHEMBL96246 | 0.92 | HRH1 (0.60) | HRH1NAAACYP1A2SMN1; SMN2CYP2C19 | |
| SCHEMBL2096007 | 0.90 | HRH1 (0.56) | HRH1NAAACYP1A2SMN1; SMN2CYP2C19 | |
| SCHEMBL4418086 | 0.89 | HRH1 (0.80) | HRH1NAAACYP1A2SMN1; SMN2CYP2C19 | |
| SCHEMBL2843489 | 0.89 | HRH1 (0.80) | HRH1NAAACYP1A2SMN1; SMN2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952316-A | FOR TREATING AUTOIMMUNE DISEASES, E.G., RHEUMATIOD ARTHRITIS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-09-14 | — | — | US | disclosed |
| EP-0627406-B1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5719176-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-02-17 | — | — | US | disclosed |
| US-5604229-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-02-18 | — | — | US | disclosed |
| EP-0627406-A1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-12-07 | — | — | EP | disclosed |