SCHEMBL8499561

SCHEMBL8499561

CCOC(=O)c1ccccc1-c1c(C(=O)O)ccc(C(=O)O)c1-c1ccccc1C(=O)OCC

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.62
KMT2A Q03164 2/20 0.57
MAPK10 P53779 2/20 0.57
MEN1 O00255 1/20 0.57
USP2 O75604 1/20 0.57
CYP1A2 P05177 1/20 0.57
CYP3A4 P08684 1/20 0.57
MAPT P10636 1/20 0.57
CYP2C9 P11712 1/20 0.57
ALOX15 P16050 1/20 0.57
CYP2C19 P33261 1/20 0.57
PTK2B Q14289 1/20 0.57
NCOA1 Q15788 1/20 0.57
NCOA3 Q9Y6Q9 1/20 0.57
ALDH1A1 P00352 5/20 0.54
HSD17B10 Q99714 2/20 0.54
MYC P01106 1/20 0.51
PDK2 Q15119 1/20 0.49
KDM4E B2RXH2 1/20 0.47
SCN1A P35498 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8499560 0.90 TSHR (0.54) TSHRKMT2AMAPK10MEN1USP2
SCHEMBL5572323 0.88 TSHR (0.69) TSHRKMT2AMAPK10MEN1USP2
SCHEMBL29617021 0.84 TSHR (0.80) TSHRKMT2AMAPK10MEN1USP2
SCHEMBL3683272 0.84 TSHR (0.80) TSHRKMT2AMAPK10MEN1USP2
SCHEMBL14181465 0.83 TSHR (0.67) TSHRKMT2AMAPK10MEN1USP2
SCHEMBL8074815 0.83 MAPT (0.53) TSHRKMT2AMAPK10MEN1USP2
SCHEMBL2129233 0.83 CDC25B (0.57) TSHRKMT2AMAPK10MEN1USP2
SCHEMBL50234 0.83 TSHR (0.84) TSHRKMT2ACYP3A4MAPTALOX15
Phthalic Acid SCHEMBL9132525 0.83 TSHR (0.84) TSHRKMT2ACYP3A4MAPTALOX15
Diethyl Phthalate SCHEMBL9132522 0.83 TSHR (0.84) TSHRKMT2ACYP3A4MAPTALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0764673-B1 Process for the production of polycarbonate TEIJIN LTD (JP) 1999-11-17 EP disclosed
US-5696222-A MELT POLYCONDENSATION OF AN AROMATIC DIHYDROXY COMPOUND AND DIPHENYLCARBONATE, THEN ADDING A SPECIFIC CARBONATE OR CARBOCYCLIC ESTER TO FORM TERMINAL BLOCKED POLYCARBONATE TEIJIN LIMITED (JP) 1997-12-09 US disclosed
EP-0764673-A2 Process for the production of polycarbonate TEIJIN LIMITED (JP) 1997-03-26 EP disclosed