Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 7/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.54 |
| ▸ | PGR | P06401 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | AR | P10275 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8503589 | 0.94 | NR3C1 (0.63) | NR3C1HIF1APGRALDH1A1LMNA | |
| SCHEMBL8499889 | 0.93 | NR3C1 (0.62) | NR3C1HIF1APGRALDH1A1LMNA | |
| SCHEMBL8499360 | 0.92 | NR3C1 (0.61) | NR3C1HIF1APGRALDH1A1LMNA | |
| SCHEMBL8501586 | 0.91 | NR3C1 (0.60) | NR3C1HIF1APGRALDH1A1LMNA | |
| SCHEMBL8500279 | 0.91 | NR3C1 (0.60) | NR3C1HIF1APGRALDH1A1LMNA | |
| SCHEMBL8499719 | 0.91 | NR3C1 (0.60) | NR3C1HIF1APGRALDH1A1LMNA | |
| SCHEMBL7204193 | 0.91 | NR3C1 (0.60) | NR3C1HIF1APGRALDH1A1LMNA | |
| SCHEMBL29714128 | 0.91 | NR3C1 (0.60) | NR3C1HIF1APGRALDH1A1LMNA | |
| Rofleponide SCHEMBL23803954 | 0.90 | NR3C1 (0.68) | NR3C1HIF1APGRLMNAAR | |
| Rofleponide SCHEMBL7196822 | 0.90 | NR3C1 (0.68) | NR3C1HIF1APGRLMNAAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5888995-A | ANTIINFLAMMATORY AND ANTIALLERGENIC AGENTS; A NOVEL GLUCOCORTICOSTEROID | ASTRA AKTIEBOLAG (SE) | 1999-03-30 | — | — | US | disclosed |
| US-5614514-A | Steroid esters | AKTIEBOLAGET ASTRA (SE) | 1997-03-25 | — | — | US | disclosed |