⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3270180 | 0.97 | — | — | |
| SCHEMBL1171485 | 0.91 | — | — | |
| SCHEMBL21779590 | 0.88 | PAOX (0.56) | — | |
| SCHEMBL15254370 | 0.88 | PAOX (0.56) | — | |
| SCHEMBL5050515 | 0.88 | PAOX (0.56) | — | |
| SCHEMBL17037791 | 0.88 | — | — | |
| SCHEMBL18383662 | 0.88 | PAOX (0.56) | — | |
| SCHEMBL17974195 | 0.80 | KDM4E (0.54) | — | |
| SCHEMBL441981 | 0.80 | — | — | |
| SCHEMBL988309 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240229026-A1 | CHIRAL CONTROL | WAVE LIFE SCIENCES LTD. (SG) | 2024-07-11 | — | — | US | disclosed |
| US-11760823-B2 | Biocompatible dendronised polymer as a non-viral transfection agent | THE UNIVERSITY OF WESTERN AUSTRALIA (AU) | 2023-09-19 | — | — | US | disclosed |
| US-11643657-B2 | Chiral control | WAVE LIFE SCIENCES LTD. (SG) | 2023-05-09 | — | — | US | disclosed |
| US-20210289794-A1 | COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE | FLAGSHIP PIONEERING INNOVATIONS V, INC. | 2021-09-23 | — | — | US | disclosed |
| US-10647747-B2 | Cyclosporin derivatives and uses thereof | S&T GLOBAL INC. (US) | 2020-05-12 | — | — | US | disclosed |
| US-20180105558-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. | 2018-04-19 | — | — | US | disclosed |
| US-20180105558-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. | 2018-04-19 | — | — | US | disclosed |
| US-9890198-B2 | Cyclosporin derivatives and uses thereof | S&T GLOBAL INC. (US) | 2018-02-13 | — | — | US | disclosed |
| US-9890198-B2 | Cyclosporin derivatives and uses thereof | S&T GLOBAL INC. (US) | 2018-02-13 | — | — | US | disclosed |
| US-20170326200-A1 | Method of Treating Prader-Willi Syndrome | FERRING B.V. (NL) | 2017-11-16 | — | — | US | disclosed |
| US-20110269709-A1 | PRODRUGS CONTAINING NOVEL BIO-CLEAVABLE LINKERS | PIRAMAL LIFE SCIENCES LIMITED | 2011-11-03 | — | — | US | disclosed |
| US-20110257343-A1 | Multifunctional Degradable Nanoparticles with Control over Size and Functionalities | VANDERBILT UNIVERSITY | 2011-10-20 | — | — | US | disclosed |
| US-20110257343-A1 | Multifunctional Degradable Nanoparticles with Control over Size and Functionalities | VANDERBILT UNIVERSITY | 2011-10-20 | — | — | US | disclosed |
| US-7932294-B2 | Prodrugs containing novel bio-cleavable linkers | APPARAO SATYAM (IN) | 2011-04-26 | — | — | US | disclosed |
| US-20090264669-A1 | Methods and Systems for Making Thiol Compounds from Terminal Olefinic Compounds | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2009-10-22 | — | — | US | disclosed |
| US-5856322-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, CARDIOVASCULAR DISORDERS | MERCK FROSST CANADA, INC. (CA) | 1999-01-05 | — | — | US | disclosed |
| EP-0480717-B1 | Unsaturated hydroxyalkylquinoline acids as leukotriene antagonists | MERCK FROSST CANADA INC (CA) | 1998-04-15 | — | — | EP | disclosed |
| US-5565473-A | USEFUL AS ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND CYTOPROTECTIVE AGENTS; MONTELUKAST AND ITS SODIUM SALT | MERCK FROSST CANADA, INC. (CA) | 1996-10-15 | — | — | US | disclosed |
| US-5270324-A | Fluorinated hydroxyalkylquinoline acids as leukotriene antagonists | MERCK FROSST CANADA, INC. (CA) | 1993-12-14 | — | — | US | disclosed |
| EP-0480717-A1 | Unsaturated hydroxyalkylquinoline acids as leukotriene antagonists | MERCK FROSST CANADA INC. (CA) | 1992-04-15 | — | — | EP | disclosed |