⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8499764 | 0.97 | — | — | |
| SCHEMBL1171485 | 0.88 | — | — | |
| SCHEMBL18383662 | 0.86 | PAOX (0.56) | — | |
| SCHEMBL15254370 | 0.86 | PAOX (0.56) | — | |
| SCHEMBL5050515 | 0.86 | PAOX (0.56) | — | |
| SCHEMBL17037791 | 0.86 | — | — | |
| SCHEMBL21779590 | 0.86 | PAOX (0.56) | — | |
| SCHEMBL17974195 | 0.78 | KDM4E (0.54) | — | |
| SCHEMBL441981 | 0.78 | — | — | |
| SCHEMBL620309 | 0.77 | ALDH1A1 (0.69) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4335509-B1 | NOVEL GLUTAMINYL CYCLASE INHIBITORS AND THE USE THEREOF IN TREATMENT OF VARIOUS DISEASES | VALENTA INTELLEKT LTD (RU) | 2026-03-11 | — | — | EP | disclosed |
| EP-3632433-B1 | NOVEL GLUTAMINYL CYCLASE INHIBITORS AND THE USE THEREOF IN TREATMENT OF VARIOUS DISEASES | NEBOLSIN VLADIMIR EVGENIEVICH (RU) | 2025-12-24 | — | — | EP | disclosed |
| US-20240238195-A1 | METHODS AND COMPOSITIONS FOR INHIBITING A NOXIOUS INSULT | PATEL ONEEL (AU) | 2024-07-18 | — | — | US | disclosed |
| US-20240114893-A1 | CORNEAL STORAGE COMPOSITIONS | AUROLAB TRUST (IN) | 2024-04-11 | — | — | US | disclosed |
| US-20240116898-A1 | NOVEL GLUTAMINYL CYCLASE INHIBITORS AND THE USE THEREOF IN TREATMENT OF VARIOUS DISEASES | LTD "VALENTA-INTELLEKT" (RU) | 2024-04-11 | — | — | US | disclosed |
| EP-4335509-A2 | NOVEL GLUTAMINYL CYCLASE INHIBITORS AND THE USE THEREOF IN TREATMENT OF VARIOUS DISEASES | LTD "VALENTA-INTELLEKT" (RU) | 2024-03-13 | — | — | EP | disclosed |
| US-11845740-B2 | Glutaminyl cyclase inhibitors and the use thereof in treatment of various diseases | LTD “Valenta-Intellekt” (RU) | 2023-12-19 | — | — | US | disclosed |
| US-20230136075-A1 | TREATMENT FOR SEPSIS-INDUCED ORGAN DYSFUNCTION | AUSTIN HEALTH (AU) | 2023-05-04 | — | — | US | disclosed |
| WO-2022243930-A1 | DISINFECTING AND CLEANING COMPOSITION COMPRISING ELECTROLYZED WATER | SWISS NEWATER HOLDING SARL (CH) | 2022-11-24 | — | — | WO | disclosed |
| US-20210212932-A1 | METHODS AND COMPOSITIONS FOR INHIBITING A NOXIOUS INSULT | PATEL ONEEL (AU) | 2021-07-15 | — | — | US | disclosed |
| WO-2000024358-A2 | SYNTHESIS AND USES OF THIOPENTONE ENANTIOMERS | THE UNIVERSITY OF SYDNEY (AU) | 2000-05-04 | — | — | WO | disclosed |
| US-4909799-A | Methods for preventing thrombosis; and surgical implant having reduced platelet deposition characteristics | THULESIUS OLAV (KW) | 1990-03-20 | — | — | US | disclosed |
| EP-0308802-A2 | Composition for preventing and treating thrombosis, and hemocompatible surgical implant therefor | Thulesius, Olav, Prof. Dr. (KW) | 1989-03-29 | — | — | EP | disclosed |
| US-4784999-A | Novel treatment | BEECHAM WUELFING GMBH & CO. KG (DE) | 1988-11-15 | — | — | US | disclosed |
| EP-0267676-A2 | Use of 1,3-di-n-butyl-7-(2-oxypropyl) xanthine in the treatment of cerebrovascular or cerebral senility associated disorders, peripheral vascular disease and proliferative skin diseases | Beecham Wuelfing GmbH & Co KG (DE) | 1988-05-18 | — | — | EP | disclosed |
| EP-0260127-A2 | Xanthine derivatives, their preparation and pharmaceutical compositions containing them | BEECHAM - WUELFING GmbH & Co. KG (DE) | 1988-03-16 | — | — | EP | disclosed |
| EP-0223811-A1 | USE OF NICORANDIL OR PINACIDIL FOR THE TREATMENT OF PERIPHERAL VASCULAR DISEASE | BEECHAM GROUP PLC (GB) | 1987-06-03 | — | — | EP | disclosed |
| WO-1986006960-A2 | USE OF NICORANDIL OR PINACIDIL FOR THE TREATMENT OF PERIPHERAL VASCULAR DISEASE | BEECHAM GROUP P.L.C. (GB) | 1986-12-04 | — | — | WO | disclosed |
| US-4452811-A | VASODILATORS | FIDIA S.P.A. (IT) | 1984-06-05 | — | — | US | disclosed |
| US-4296039-A | REACTING 2-HALORESORCINOLS OR THEIR MONOETHERS WITH BETA-KETO ESTERS | FIDIA S.P.A. (IT) | 1981-10-20 | — | — | US | disclosed |