Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3112777 | 0.85 | CYP2C19 (0.47) | CYP2C19HIF1ATAAR1HDAC3HDAC4 | |
| SCHEMBL8499984 | 0.83 | ACACB (0.51) | CYP2C19HIF1ATAAR1HDAC3HDAC4 | |
| SCHEMBL9517017 | 0.81 | MAPT (0.50) | CYP2C19HIF1ATAAR1HDAC3HDAC4 | |
| SCHEMBL17662698 | 0.80 | KCNN4 (0.47) | CYP2C19HIF1ATAAR1HDAC3HDAC4 | |
| SCHEMBL2332445 | 0.80 | PRSS1 (0.61) | — | |
| SCHEMBL19747523 | 0.79 | HDAC3 (0.44) | CYP2C19HIF1ATAAR1HDAC3HDAC4 | |
| SCHEMBL9354938 | 0.79 | CNR1 (0.42) | CYP2C19HIF1ATAAR1HDAC3HDAC4 | |
| SCHEMBL630419 | 0.77 | IDO1 (0.47) | CYP2C19HIF1AKMT2A | |
| SCHEMBL7739108 | 0.76 | CYP2C19 (0.61) | CYP2C19HIF1ATAAR1HDAC3HDAC4 | |
| SCHEMBL20350427 | 0.76 | GAA (0.49) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0938494-A1 | INHIBITORS OF PROTEIN FARNESYL TRANSFERASE | WARNER-LAMBERT COMPANY (US) | 1999-09-01 | — | — | EP | disclosed |
| WO-1997044350-A1 | INHIBITORS OF PROTEIN FARNESYL TRANSFERASE | WARNER-LAMBERT COMPANY (US) | 1997-11-27 | — | — | WO | disclosed |