Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3112777 | 0.85 | CYP2C19 (0.47) | MAPTKMT2ATAAR1CYP2C19HIF1A | |
| SCHEMBL8499984 | 0.83 | ACACB (0.51) | TAAR1CHRM2CHRM1CHRM3CYP2C19 | |
| SCHEMBL4231538 | 0.82 | BCAT2 (0.47) | MAPTKMT2ACHRM2CHRM1CHRM3 | |
| SCHEMBL11491536 | 0.81 | TAAR1 (0.48) | MAPTKMT2ATAAR1CYP2C19LMNA | |
| SCHEMBL8499982 | 0.81 | CYP2C19 (0.44) | MAPTKMT2ATAAR1CYP2C19HIF1A | |
| SCHEMBL20909439 | 0.81 | BCAT2 (0.46) | MAPTKMT2ACHRM2CHRM1CHRM3 | |
| SCHEMBL17662698 | 0.80 | KCNN4 (0.47) | TAAR1CYP2C19HIF1AHDAC3HDAC4 | |
| SCHEMBL2332445 | 0.80 | PRSS1 (0.61) | LMNA | |
| SCHEMBL10843770 | 0.80 | ALDH1A1 (0.50) | MAPTKMT2ALMNA | |
| SCHEMBL3901654 | 0.79 | LMNA (0.48) | MAPTKMT2ACHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0344425-B1 | N-[[(2,6-disubstituted)phenyl]-N'- arylalkyl] ureas as antihypercholesterolemic and antiatherosclerotic agents | WARNER LAMBERT CO (US) | 1993-12-08 | — | — | EP | claimed |
| EP-0344425-A2 | N-[[(2,6-disubstituted)phenyl]-N'- arylalkyl] ureas as antihypercholesterolemic and antiatherosclerotic agents | WARNER-LAMBERT COMPANY (US) | 1989-12-06 | — | — | EP | claimed |
| CN-109641857-A | Phenyl Urea Derivatives as N- formyl peptide receptor regulator | 阿勒根公司 | 2019-04-16 | — | — | CN | disclosed |
| EP-0344425-B1 | N-[[(2,6-disubstituted)phenyl]-N'- arylalkyl] ureas as antihypercholesterolemic and antiatherosclerotic agents | WARNER LAMBERT CO (US) | 1993-12-08 | — | — | EP | disclosed |
| EP-0344425-A2 | N-[[(2,6-disubstituted)phenyl]-N'- arylalkyl] ureas as antihypercholesterolemic and antiatherosclerotic agents | WARNER-LAMBERT COMPANY (US) | 1989-12-06 | — | — | EP | disclosed |