Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.38 |
| ▸ | STK17B | O94768 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17186331 | 0.88 | TAAR1 (0.67) | PNMTTAAR1SIGMAR1CYP3A4GLA | |
| SCHEMBL12719081 | 0.82 | SKP2 (0.56) | SIGMAR1CYP3A4GLASMN1; SMN2NPSR1 | |
| SCHEMBL5146820 | 0.82 | SKP2 (0.50) | TAAR1ALDH1A1SKP2CYP1A2CYP2D6 | |
| SCHEMBL4037320 | 0.82 | PNMT (0.76) | PNMTTAAR1SIGMAR1ALDH1A1IGF1R | |
| SCHEMBL80740 | 0.81 | SKP2 (0.42) | PNMTTAAR1SIGMAR1CYP3A4ALDH1A1 | |
| SCHEMBL82284 | 0.81 | IGF1R (0.44) | PNMTTAAR1SIGMAR1CYP3A4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL14829816 | 0.80 | PNMT (0.73) | PNMTTAAR1SIGMAR1CYP3A4GLA | |
| Hydrochloric Acid SCHEMBL5146884 | 0.80 | SKP2 (0.48) | TAAR1GLAALDH1A1SKP2CYP1A2 | |
| SCHEMBL109221 | 0.79 | CYP3A4 (0.52) | PNMTTAAR1CYP3A4ALDH1A1NPSR1 | |
| SCHEMBL29487211 | 0.79 | CYP3A4 (0.52) | PNMTTAAR1CYP3A4ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735018-B1 | N-(alpha-alkylbenzylidene)-alpha-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor | SUMITOMO CHEMICAL CO (JP) | 1999-07-21 | — | — | EP | disclosed |
| EP-0735018-A1 | N-(alpha-alkylbenzylidene)-alpha-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |