⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7077119 | 0.97 | — | — | |
| SCHEMBL3074621 | 0.97 | — | — | |
| Benzene SCHEMBL8022388 | 0.95 | ALDH1A1 (0.33) | — | |
| SCHEMBL28139668 | 0.72 | ALDH1A1 (0.55) | — | |
| SCHEMBL16031 | 0.72 | — | — | |
| SCHEMBL3096628 | 0.72 | — | — | |
| SCHEMBL11481750 | 0.71 | — | — | |
| SCHEMBL28790559 | 0.70 | ALDH1A1 (0.46) | — | |
| Hydrochloric Acid SCHEMBL1162175 | 0.70 | ALDH1A1 (0.52) | — | |
| SCHEMBL28372761 | 0.70 | ALDH1A1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170079252-A1 | NOVEL GERM CELL ABLATION COMPOUNDS AND USES THEREOF | THE GENERAL HOSPITAL CORPORATION (US) | 2017-03-23 | — | — | US | claimed |
| US-9538734-B2 | Germ cell ablation compounds and uses thereof | THE GENERAL HOSPITAL CORPORATION (US) | 2017-01-10 | — | — | US | claimed |
| US-20170079252-A1 | NOVEL GERM CELL ABLATION COMPOUNDS AND USES THEREOF | THE GENERAL HOSPITAL CORPORATION (US) | 2017-03-23 | — | — | US | disclosed |
| US-9538734-B2 | Germ cell ablation compounds and uses thereof | THE GENERAL HOSPITAL CORPORATION (US) | 2017-01-10 | — | — | US | disclosed |
| US-20140261212-A1 | NOVEL GERM CELL ABLATION COMPOUNDS AND USES THEREOF | THE GENERAL HOSPITAL CORPORATION (US) | 2014-09-18 | — | — | US | disclosed |
| US-5939290-A | Modified sialyl Lewisx compounds | ALBERTA RESEARCH COUNCIL (CA) | 1999-08-17 | — | — | US | disclosed |
| US-5759993-A | OLIGOSACCHARIDES AS IMMUNOMODULATORS | ALBERTA RESEARCH COUNCIL (CA) | 1998-06-02 | — | — | US | disclosed |
| EP-0589951-A1 | MODIFIED SIALYL LEWIS?X COMPOUNDS | GLYCOMED INCORPORATED (US) | 1994-04-06 | — | — | EP | disclosed |
| WO-1992022565-A1 | MODIFIED SIALYL LEWISX COMPOUNDS | ALBERTA RESEARCH COUNCIL (CA) | 1992-12-23 | — | — | WO | disclosed |