SCHEMBL8500449

SCHEMBL8500449

CCCCCCCCC=CCCCCCCC/C=C1/C[C@@](CO)(COC(C)=O)OC1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ PRKCA P17252 18/20 1.00
▸ PRKCE Q02156 2/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8500456 1.00 PRKCA (1.00) PRKCAPRKCE
SCHEMBL8507045 1.00 PRKCA (1.00) PRKCAPRKCE
SCHEMBL8507047 1.00 PRKCA (1.00) PRKCAPRKCE
SCHEMBL8349589 0.97 PRKCA (1.00) PRKCA
SCHEMBL8349585 0.97 PRKCA (1.00) PRKCA
SCHEMBL8353793 0.97 PRKCA (1.00) PRKCA
SCHEMBL8528951 0.74 PRKCA (1.00) PRKCA
SCHEMBL8531712 0.74 PRKCA (1.00) PRKCA
SCHEMBL8531709 0.74 PRKCA (1.00) PRKCA
SCHEMBL8528945 0.74 PRKCA (1.00) PRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5874464-A ANTAGONIST OF PROTEIN KINASE C THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1999-02-23 — — US disclosed
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