Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | NAMPT | P43490 | 16/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7215175 | 0.94 | NAMPT (0.44) | NAMPT | |
| SCHEMBL8503014 | 0.88 | PTGS2 (0.37) | PTGS2NAMPTADORA1 | |
| SCHEMBL7216105 | 0.87 | PTGS2 (0.54) | PTGS2ADORA1 | |
| SCHEMBL7210277 | 0.83 | PTGS2 (0.56) | PTGS2ADORA1 | |
| SCHEMBL7210164 | 0.81 | PTGS2 (0.49) | PTGS2ADORA1 | |
| Dimethylamine SCHEMBL7210227 | 0.80 | PTGS2 (0.56) | PTGS2ADORA1 | |
| SCHEMBL7210483 | 0.80 | PTGS2 (0.55) | PTGS2ADORA1 | |
| SCHEMBL7215116 | 0.79 | PTGS2 (0.58) | PTGS2ADORA1 | |
| SCHEMBL7210115 | 0.78 | PTGS2 (0.47) | PTGS2ADORA1 | |
| SCHEMBL27530526 | 0.78 | PTGS2 (0.46) | PTGS2ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948497-A2 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND THEIR USE | Amgen inc. (US) | 1999-10-13 | — | — | EP | disclosed |
| WO-1998024782-A2 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND THEIR USE | AMGEN INC. (US) | 1998-06-11 | — | — | WO | disclosed |