Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL840398 | 1.00 | GCK (0.80) | GCKKCNH2 | |
| SCHEMBL839672 | 0.97 | GCK (0.79) | GCKKCNH2 | |
| SCHEMBL839673 | 0.97 | GCK (0.79) | GCKKCNH2 | |
| SCHEMBL840374 | 0.92 | GCK (0.80) | GCKKCNH2 | |
| SCHEMBL850247 | 0.92 | GCK (0.80) | GCKKCNH2 | |
| SCHEMBL839082 | 0.92 | GCK (0.81) | GCKKCNH2 | |
| SCHEMBL850271 | 0.92 | GCK (0.81) | GCKKCNH2 | |
| SCHEMBL838234 | 0.91 | GCK (0.79) | GCKKCNH2 | |
| SCHEMBL840045 | 0.90 | GCK (0.80) | GCKKCNH2 | |
| SCHEMBL850743 | 0.90 | GCK (0.80) | GCKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143263-B2 | Therapeutic agents | ASTRAZENECA AB (SE) | 2012-03-27 | — | — | US | disclosed |
| US-20100093757-A1 | THERAPEUTIC AGENTS 414 | ASTRAZENECA AB (SE) | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093757-A1 | THERAPEUTIC AGENTS 414 | GCK, GCKR, GPR119 | GCK 1/4885KCNH2 1438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.