Phosphoric Acid

SCHEMBL8501040

O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O.O=P([O-])([O-])[O-].O=P([O-])([O-])[O-].O=P([O-])([O-])[O-].O=P([O-])([O-])[O-].O=P([O-])([O-])[O-].O=P([O-])([O-])[O-].O=P([O-])([O-])[O-].O=P([O-])([O-])[O-].O=P([O-])([O-])[O-].O=P([O-])([O-])[O-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2]

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA1A ADRA1B ADRA1D ADRB1 ADRB2 ADRB3 CYP11B1 DPP4 FGFR1 FGFR2 FGFR3 FGFR4 HRH1 JAK1 JAK2 JAK3 KCNA1 KCNA10 KCNA2 KCNA3 KCNA4 KCNA5 KCNA6 KCNA7 KCNB1 KCNB2 KCNC1 KCNC2 KCNC3 KCNC4 KCND1 KCND2 KCND3 KCNF1 KCNG1 KCNG2 KCNG3 KCNG4 KCNH1 KCNH2 KCNH3 KCNH4 KCNH5 KCNH6 KCNH7 KCNH8 KCNQ1 KCNQ2 KCNQ3 KCNQ4 KCNQ5 KCNS1 KCNS2 KCNS3 KCNV1 KCNV2 KDR KIT NA OPRD1 OPRK1 OPRM1 P PDGFRB PIK3CD SCN10A SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SMO TYK2 pol rplA rplB rplC rplD rplE rplF rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmC rpmD rpmE rpmF rpmG rpmH rpmI rpmJ rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsS rpsT rpsU ykgM ykgO

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	SLC34A1	Q06495	1/20	0.58

▸	LMNA	P02545	3/20	0.40

▸	KDM4E	B2RXH2	2/20	0.39

▸	CYP2C19	P33261	1/20	0.39

▸	KMT2A	Q03164	1/20	0.39

▸	CA2	P00918	1/20	0.39

▸	TYMS	P04818	1/20	0.38

▸	FDPS	P14324	3/20	0.35

▸	BLM	P54132	2/20	0.33

▸	MMP2	P08253	1/20	0.33

▸	THRB	P10828	1/20	0.33

▸	MAPK1	P28482	1/20	0.33

▸	HSD17B10	Q99714	1/20	0.33

▸	TDP1	Q9NUW8	1/20	0.33

▸	PDE3A	Q14432	1/20	0.30

▸	CA1	P00915	2/20	0.30

▸	CA4	P22748	2/20	0.30

▸	CA5A	P35218	2/20	0.30

▸	CA5B	Q9Y2D0	2/20	0.30

▸	CYP3A4	P08684	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Phosphoric Acid SCHEMBL4630042	1.00	SLC34A1 (0.58)	SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL621306	1.00	SLC34A1 (0.58)	SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL2822272	1.00	SLC34A1 (0.58)	SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL6226482	1.00	SLC34A1 (0.58)	SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL3469432	1.00	SLC34A1 (0.58)	SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL3406130	1.00	SLC34A1 (0.58)	SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL17925459	1.00	SLC34A1 (0.58)	SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL2025378	0.95	SLC34A1 (0.54)	SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL5635467	0.95	SLC34A1 (0.54)	SLC34A1LMNAKDM4ECYP2C19KMT2A
Phosphoric Acid SCHEMBL8508247	0.95	SLC34A1 (0.67)	SLC34A1LMNAKDM4ECYP2C19KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5958445-A	ORGANOLEPTICALLY ACCEPTABLE ANTIINFLAMMATORY AGENT;VETERINARY DRUG; FOR ORAL ADMINISTRATION	AMERICAN HOME PRODUCTS CORPORATION (US)	1999-09-28	—	—	US	disclosed
US-5780046-A	ADMINISTERING IN COMBINATION WITH AN ACIDIC COMPONENT TO IMPROVE TASTE	AMERICAN HOME PRODUCTS CORPORATION (US)	1998-07-14	—	—	US	disclosed