Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 5/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ADH1B | P00325 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | ADH4 | P08319 | 1/20 | 0.39 |
| ▸ | ADH7 | P40394 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7101242 | 0.90 | — | — | |
| SCHEMBL1932673 | 0.79 | OPRM1 (0.48) | OPRM1FAAHCNR1CNR2SPHK1 | |
| SCHEMBL1311730 | 0.79 | OPRM1 (0.48) | OPRM1FAAHCNR1CNR2SPHK1 | |
| SCHEMBL31121318 | 0.79 | OPRM1 (0.48) | OPRM1FAAHCNR1CNR2SPHK1 | |
| SCHEMBL6420889 | 0.79 | OPRM1 (0.48) | OPRM1FAAHCNR1CNR2SPHK1 | |
| SCHEMBL7757207 | 0.79 | OPRM1 (0.48) | OPRM1FAAHCNR1CNR2SPHK1 | |
| SCHEMBL1932307 | 0.79 | OPRM1 (0.48) | OPRM1FAAHCNR1CNR2SPHK1 | |
| SCHEMBL5012572 | 0.79 | OPRM1 (0.48) | OPRM1FAAHCNR1CNR2SPHK1 | |
| SCHEMBL534657 | 0.79 | OPRM1 (0.48) | OPRM1FAAHCNR1CNR2SPHK1 | |
| SCHEMBL1930626 | 0.79 | OPRM1 (0.48) | OPRM1FAAHCNR1CNR2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5886175-A | TETRACYCLINE ANTIBIOTICS | AMERICAN CYANAMID COMPANY (US) | 1999-03-23 | — | — | US | disclosed |
| US-5512553-A | PREVENTING OR TREATING BACTERIAL INFECTIONS | AMERICAN CYANAMID COMPANY (US) | 1996-04-30 | — | — | US | disclosed |