SCHEMBL8501135

SCHEMBL8501135

CC=Cc1cc(C(F)(c2ccc(OS(C)(=O)=O)c(C=CC)c2)C(F)(F)C(F)(F)F)ccc1OS(C)(=O)=O

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
HMGCR P04035 1/20 0.31
CYP3A4 P08684 1/20 0.31
PDE4B Q07343 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3839690 0.86 CA1 (0.34) CA1CA2CA9HMGCRCYP3A4
SCHEMBL3839693 0.86 CA1 (0.34) CA1CA2CA9HMGCRCYP3A4
SCHEMBL8502123 0.84 ALDH1A1 (0.43)
SCHEMBL3838171 0.82 CA1 (0.40) CA1CA2CA9HMGCRCYP3A4
SCHEMBL3838169 0.82 CA1 (0.40) CA1CA2CA9HMGCRCYP3A4
SCHEMBL3839796 0.77 CA1 (0.36) CA1CA2CA9HMGCRCYP3A4
SCHEMBL3839800 0.77 CA1 (0.36) CA1CA2CA9HMGCRCYP3A4
SCHEMBL3844451 0.75 HMGCR (0.39) CA1CA2CA9HMGCRCYP3A4
SCHEMBL3844448 0.75 HMGCR (0.39) CA1CA2CA9HMGCRCYP3A4
SCHEMBL3846194 0.75 HMGCR (0.32) CA1CA2CA9HMGCRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0956312-A1 PROCESS FOR PRODUCING PHENYLENE-CONTAINING POLYMER AND FILM-FORMING MATERIAL JSR Corporation (JP) 1999-11-17 EP disclosed
WO-1998033836-A1 PROCESS FOR PRODUCING PHENYLENE-CONTAINING POLYMER AND FILM-FORMING MATERIAL JSR CORPORATION (JP) 1998-08-06 WO disclosed