Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.82 |
| ▸ | LMNA | P02545 | 3/20 | 0.82 |
| ▸ | CCR1 | P32246 | 3/20 | 0.82 |
| ▸ | CCR5 | P51681 | 3/20 | 0.82 |
| ▸ | CCR8 | P51685 | 3/20 | 0.82 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.82 |
| ▸ | POLB | P06746 | 1/20 | 0.82 |
| ▸ | METAP1 | P53582 | 1/20 | 0.82 |
| ▸ | BLM | P54132 | 1/20 | 0.82 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.82 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.82 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.82 |
| ▸ | NPC1 | O15118 | 6/20 | 0.67 |
| ▸ | TP53 | P04637 | 4/20 | 0.67 |
| ▸ | RAB9A | P51151 | 4/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dipyridyl SCHEMBL27651116 | 0.91 | KDM4E (0.88) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL28760321 | 0.91 | KDM4E (0.88) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL5922 | 0.91 | KDM4E (1.00) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL29907716 | 0.91 | KDM4E (1.00) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL3711450 | 0.91 | KDM4E (1.00) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL29351528 | 0.91 | KDM4E (1.00) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL27594936 | 0.88 | KDM4E (0.82) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL6392378 | 0.88 | KDM4E (0.82) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL1535115 | 0.88 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL11114417 | 0.88 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105669803-A | KETOLIDE COMPOUNDS | 沃克哈特有限公司 | 2016-06-15 | — | — | CN | disclosed |
| CN-103384676-B | Ketolactone compounds | WOCKHARDT LTD. (IN) | 2016-02-03 | — | — | CN | disclosed |
| CN-103384676-A | Ketolactone compounds | WOCKHARDT LTD | 2013-11-06 | — | — | CN | disclosed |
| US-5981286-A | USED AS LUMINESCENT MARKER GROUPS IN IMMUNOASSAYS; A LANTHANIDE OR TRANSITIONAL METAL COMPLEX CONTAINING ATLEAST TWO NITROGEN CONTAINING HETEROCYCLIC LIGAND ATTACHED TO METAL VIA NITROGEN ATOM, A REACTIVE GROUP, A HYDROPHILIC GROUP | ROCHE DIAGNOSTICS, GMBH (DE) | 1999-11-09 | — | — | US | disclosed |