Dipyridyl

Dipyridyl

SCHEMBL1535115

[Ni].c1ccc(-c2ccccn2)nc1.c1ccc(-c2ccccn2)nc1

nearest known ligand 0.93

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.93
LMNA P02545 3/20 0.93
CCR1 P32246 3/20 0.93
CCR5 P51681 3/20 0.93
CCR8 P51685 3/20 0.93
CYP1A2 P05177 1/20 0.93
POLB P06746 1/20 0.93
METAP1 P53582 1/20 0.93
BLM P54132 1/20 0.93
HIF1A Q16665 1/20 0.93
DOHH Q9BU89 1/20 0.93
P4HTM Q9NXG6 1/20 0.93
NPC1 O15118 6/20 0.74
TP53 P04637 4/20 0.74
RAB9A P51151 4/20 0.74
ALOX15 P16050 3/20 0.74
SMN1; SMN2 Q16637 3/20 0.74
L3MBTL1 Q9Y468 3/20 0.74
HTT P42858 2/20 0.74
TDP1 Q9NUW8 2/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dipyridyl SCHEMBL7900008 1.00 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL287597 1.00 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL7904091 0.97 KDM4E (0.88) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL809478 0.97 KDM4E (0.88) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL809361 0.97 KDM4E (0.88) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL286888 0.97 KDM4E (0.88) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL2207183 0.97 KDM4E (0.88) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL29351528 0.97 KDM4E (1.00) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL3711450 0.97 KDM4E (1.00) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL29907716 0.97 KDM4E (1.00) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108473450-B Process for preparing 1,1, 3-trioxo-1, 2-benzothiazole-6-carboxamides 阿达玛阿甘股份有限公司 2022-05-10 CN claimed
JP-4657390-B2 2011-03-23 JP claimed
US-20040023092-A1 Ionic perfluorovinyl compounds and their uses as components of ionic conductors of the polymer type, of selective membranes or of catalysts ACEP INC. (CA) 2004-02-05 US claimed
US-20020193540-A1 Ionic perfluorovinyl compounds and their uses as components of ionic conductors of the polymer type, of selective membranes or of catalysts ARMAND MICHEL (CA) 2002-12-19 US claimed
US-20020026021-A1 Ionic perfluorovinyl compounds and their uses as components of ionic conductors of the polymer type, of selective membranes or of catalysts ARMAND MICHEL (CA) 2002-02-28 US claimed
JP-2001509818-A 2001-07-24 JP claimed
EP-0968196-A1 PERFLUOROVINYL IONIC COMPOUNDS AND THEIR USE IN CONDUCTIVE MATERIALS ACEP INC. (CA) 2000-01-05 EP claimed
WO-1999005126-A1 PERFLUOROVINYL IONIC COMPOUNDS AND THEIR USE IN CONDUCTIVE MATERIALS ACEP INC. (CA) 1999-02-04 WO claimed
CN-116615407-A Method for producing raspberry ketone 罗地亚经营管理公司 2023-08-18 CN disclosed
CN-108473450-B Process for preparing 1,1, 3-trioxo-1, 2-benzothiazole-6-carboxamides 阿达玛阿甘股份有限公司 2022-05-10 CN disclosed
CN-106478397-B For producing alkoxy phenol and alkoxy-hydroxy benzaldehyde method 罗地亚运作公司 2019-08-30 CN disclosed
CN-104203891-B Process for producing alkoxy-hydroxybenzaldehydes substantially free of alkyl-alkoxy-hydroxybenzaldehydes 罗地亚运作公司 2019-03-15 CN disclosed
CN-108473450-A The preparation method of 1,1,3- trioxy- -1,2- benzothiazole -6- formamides 阿达玛阿甘股份有限公司 2018-08-31 CN disclosed
US-7271228-B2 Ionic perfluorovinyl compounds and their uses as components of ionic conductors of the polymer type, of selective membranes or of catalysts ACEP INC. (CA) 2007-09-18 US disclosed
US-20020193540-A1 Ionic perfluorovinyl compounds and their uses as components of ionic conductors of the polymer type, of selective membranes or of catalysts ARMAND MICHEL (CA) 2002-12-19 US disclosed
US-6426397-B1 Ionic perfluorovinyl compounds and their uses as components of ionic conductors of the polymer type, of selective membranes or of catalysts ACEP INC. (CA) 2002-07-30 US disclosed
US-20020026021-A1 Ionic perfluorovinyl compounds and their uses as components of ionic conductors of the polymer type, of selective membranes or of catalysts ARMAND MICHEL (CA) 2002-02-28 US disclosed
US-6288187-B1 CROSSLINKED ANIONIC POLYMER; ELECTROLYTES; PERMSELECTIVE MEMBRANES ACEP INC. (CA) 2001-09-11 US disclosed
EP-1086080-A1 DIARYLSELENIDE COMPOUNDS AND THEIR USE IN HUMAN OR VETERINARY MEDICINE AND IN COSMETICS Galderma Research & Development, S.N.C. (FR) 2001-03-28 EP disclosed
WO-1999065872-A1 DIARYLSELENIDE COMPOUNDS AND THEIR USE IN HUMAN OR VETERINARY MEDICINE AND IN COSMETICS GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) 1999-12-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020193540-A1 Ionic perfluorovinyl compounds and their uses as components of ionic conductors of the polymer type, of selective membranes or of catalysts CCNO, SCO2, CNR2 KDM4E 3725/4885LMNA 1024/4885CCR1 205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.