Propionic Acid

Propionic Acid

SCHEMBL8501295

CCC(=O)O.CCC(CO)(CO)CO.COC

nearest known ligand 0.48

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Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 2/20 0.48
HDAC3 O15379 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
ALDH1A1 P00352 2/20 0.30
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30
MAPK1 P28482 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HIF1A Q16665 1/20 0.30
MEN1 O00255 1/20 0.30
CYP1A2 P05177 1/20 0.30
THRB P10828 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propionic Acid SCHEMBL6395282 1.00 FFAR3 (0.48) FFAR3HDAC3HDAC1HDAC2HDAC8
Propionic Acid SCHEMBL28034572 0.93 FFAR3 (0.56) FFAR3HDAC3HDAC1HDAC2HDAC8
Propionic Acid SCHEMBL28193865 0.93 FFAR3 (0.56) FFAR3HDAC3HDAC1HDAC2HDAC8
Propionic Acid SCHEMBL30166958 0.93 FFAR3 (0.56) FFAR3HDAC3HDAC1HDAC2HDAC8
Propionic Acid SCHEMBL30607252 0.88 FFAR3 (0.50) FFAR3HDAC3HDAC1HDAC2HDAC8
Methoxymethane SCHEMBL935937 0.84 ALDH1A1 (0.35) ALDH1A1
Propionic Acid SCHEMBL2160998 0.84 FFAR3 (0.46) FFAR3
SCHEMBL8777802 0.83 FFAR3 (0.36) FFAR3ALDH1A1TP53CYP3A4MAPK1
Glycolic Acid SCHEMBL11515137 0.82 FFAR3 (0.40) FFAR3HDAC3HDAC1HDAC2HDAC8
Propionic Acid SCHEMBL8927677 0.82 FFAR3 (0.62) FFAR3HDAC3HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0963390-A1 PHOTOCHROMIC POLYURETHANE COATING AND ARTICLES HAVING SUCH A COATING PPG Industries Ohio, Inc. (US) 1999-12-15 EP disclosed
WO-1998037115-A1 PHOTOCHROMIC POLYURETHANE COATING AND ARTICLES HAVING SUCH A COATING PPG INDUSTRIES OHIO, INC. (US) 1998-08-27 WO disclosed