Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 6/20 | 0.61 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.61 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.46 |
| ▸ | TUBB | P07437 | 2/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL7254766 | 0.82 | ALDH1A1 (0.76) | ALDH1A1LMNAHTTL3MBTL1TUBB4A | |
| SCHEMBL14375516 | 0.80 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL29884026 | 0.80 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL7247673 | 0.79 | PDE4A (0.61) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL20698423 | 0.79 | ALDH1A1 (0.65) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL12677583 | 0.78 | TUBB1 (0.69) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL4823462 | 0.78 | PDE4A (0.73) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL8793402 | 0.76 | ALDH1A1 (0.83) | ALDH1A1LMNAHTTL3MBTL1TUBB4A | |
| Dimethylamine SCHEMBL8525990 | 0.76 | ALDH1A1 (0.40) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL4819788 | 0.76 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414730-B1 | Chemical Compounds and pharmaceutical compositions capable of releasing a drug | MILLS RANDELL L (US) | 1999-12-15 | — | — | EP | disclosed |