Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 2/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8620233 | 0.89 | TSHR (0.44) | TSHRHPGDFAAHPRKCAPRKCD | |
| SCHEMBL4202560 | 0.89 | TSHR (0.58) | TSHRHPGDFAAHPLA2G2CPRKCA | |
| SCHEMBL9186055 | 0.88 | TSHR (0.54) | TSHRHPGDFAAHPLA2G2CPRKCA | |
| SCHEMBL5336277 | 0.87 | ALDH1A1 (0.41) | TSHRHPGDPLA2G2CPRKCAPRKCD | |
| SCHEMBL29362857 | 0.87 | TSHR (0.42) | TSHRHPGDFAAHPLA2G2CPRKCA | |
| SCHEMBL5477404 | 0.86 | TSHR (0.60) | TSHRHPGDFAAHPLA2G2CTHRB | |
| SCHEMBL5270024 | 0.86 | TSHR (0.60) | TSHRHPGDFAAHPLA2G2CTHRB | |
| SCHEMBL7647460 | 0.85 | TSHR (0.48) | TSHRHPGDFAAHPRKCAPRKCD | |
| SCHEMBL29026124 | 0.85 | TSHR (0.39) | TSHRHPGDFAAHPRKCAPRKCD | |
| SCHEMBL28122605 | 0.84 | TSHR (0.49) | TSHRHPGDPRKCAPRKCDCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902800-A1 | SURFACTANT-CONTAINING ACETOACETOXY-FUNCTIONAL AND ENAMINE-FUNCTIONAL POLYMERS | EASTMAN CHEMICAL COMPANY (US) | 1999-03-24 | — | — | EP | claimed |
| WO-1997045468-A1 | SURFACTANT-CONTAINING ACETOACETOXY-FUNCTIONAL AND ENAMINE-FUNCTIONAL POLYMERS | EASTMAN CHEMICAL COMPANY (US) | 1997-12-04 | — | — | WO | claimed |