SCHEMBL8501668

SCHEMBL8501668

[CH2]OP(=O)(O)OC(c1ccccc1)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SRC P12931 2/20 0.45
ACP3 P15309 5/20 0.40
POLB P06746 2/20 0.40
PGK1 P00558 1/20 0.37
PGK2 P07205 1/20 0.37
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10534552 0.88 SRC (0.52) SRCACP3POLBPGK1PGK2
SCHEMBL28479995 0.81 SRC (0.45) SRCACP3POLBPGK1PGK2
SCHEMBL28251016 0.81 SRC (0.45) SRCACP3POLBPGK1PGK2
SCHEMBL613995 0.79 SRC (0.52) SRCACP3POLBPGK1PGK2
SCHEMBL10714749 0.79 POLB (0.60) SRCACP3POLB
SCHEMBL27723605 0.76 SRC (0.48) SRCACP3POLBPGK1PGK2
SCHEMBL28479993 0.76 SRC (0.48) SRCACP3POLBPGK1PGK2
SCHEMBL2819699 0.74 SRC (0.44) SRCACP3POLB
SCHEMBL16428475 0.74 ALDH1A1 (0.47) SRCACP3POLBPGK1PGK2
SCHEMBL28641739 0.74 TSHR (0.40) SRCACP3POLBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5939405-A Phosphate derivatives of diaryl 1,3,4-oxadiazolone BRISTOL-MYERS SQUIBB COMPANY (US) 1999-08-17 US disclosed