SCHEMBL8501690

SCHEMBL8501690

CC(CC(F)(F)F)C1=NC(=O)NC1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL1099725 0.68 DPP4 (0.31)
SCHEMBL29068174 0.59 TSHR (0.36)
SCHEMBL22746729 0.56 NAALAD2 (0.35)
SCHEMBL17927924 0.55
SCHEMBL21758880 0.55
SCHEMBL24119174 0.54
SCHEMBL193951 0.54
SCHEMBL6850213 0.54
SCHEMBL824112 0.52
SCHEMBL24275751 0.52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0946559-A2 IMIDAZOPYRIDAZINES Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 1999-10-06 EP disclosed
WO-1998028299-A2 IMIDAZOPYRIDAZINES BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1998-07-02 WO disclosed