Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.74 |
| ▸ | DPP7 | Q9UHL4 | 14/20 | 0.74 |
| ▸ | DPP8 | Q6V1X1 | 13/20 | 0.74 |
| ▸ | DPP9 | Q86TI2 | 13/20 | 0.74 |
| ▸ | FAP | Q12884 | 10/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5713150 | 0.96 | DPP4 (0.80) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL5713152 | 0.96 | DPP4 (0.80) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL7298604 | 0.96 | DPP4 (0.80) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL2195630 | 0.96 | DPP4 (0.80) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL27452954 | 0.96 | DPP4 (0.80) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL2182020 | 0.96 | DPP4 (0.80) | DPP4DPP7DPP8DPP9FAP | |
| Hydrochloric Acid SCHEMBL7309557 | 0.88 | DPP4 (0.91) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL2183274 | 0.87 | DPP4 (0.67) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL10792312 | 0.85 | DPP4 (0.67) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL6453066 | 0.85 | DPP4 (1.00) | DPP4DPP7DPP8DPP9FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0914608-A1 | MICROPLATE THERMAL SHIFT ASSAY AND APPARATUS FOR LIGAND DEVELOPMENT AND MULTI-VARIABLE PROTEIN CHEMISTRY OPTIMIZATION | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1999-05-12 | — | — | EP | disclosed |
| WO-1997042500-A1 | MICROPLATE THERMAL SHIFT ASSAY AND APPARATUS FOR LIGAND DEVELOPMENT AND MULTI-VARIABLE PROTEIN CHEMISTRY OPTIMIZATION | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1997-11-13 | — | — | WO | disclosed |