SCHEMBL5713152

SCHEMBL5713152

N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1[C]=O

nearest known ligand 0.80

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 20/20 0.80
DPP8 Q6V1X1 14/20 0.80
DPP9 Q86TI2 14/20 0.80
DPP7 Q9UHL4 14/20 0.80
FAP Q12884 10/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7298604 1.00 DPP4 (0.80) DPP4DPP8DPP9DPP7FAP
SCHEMBL27452954 1.00 DPP4 (0.80) DPP4DPP8DPP9DPP7FAP
SCHEMBL2182020 1.00 DPP4 (0.80) DPP4DPP8DPP9DPP7FAP
SCHEMBL2195630 1.00 DPP4 (0.80) DPP4DPP8DPP9DPP7FAP
SCHEMBL5713150 1.00 DPP4 (0.80) DPP4DPP8DPP9DPP7FAP
SCHEMBL8501824 0.96 DPP4 (0.74) DPP4DPP8DPP9DPP7FAP
SCHEMBL2183274 0.91 DPP4 (0.67) DPP4DPP8DPP9DPP7FAP
SCHEMBL10792312 0.89 DPP4 (0.67) DPP4DPP8DPP9DPP7FAP
SCHEMBL6453066 0.89 DPP4 (1.00) DPP4DPP8DPP9DPP7FAP
SCHEMBL7298573 0.87 DPP4 (0.62) DPP4DPP8DPP9DPP7FAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105705034-A Improved meat slurry methods of production and compositions 微自然有限责任公司 2016-06-22 CN claimed
EP-1245568-B1 Sulfonyl derivatives of amino acids and their use as inhibitors of dipeptidyl-peptidase IV (DPP IV) SERVIER LAB (FR) 2006-01-18 EP claimed
US-6716843-B2 INHIBITOR OF DIPEPTIDYL-PEPTIDASE IV LES LABORATOIRES SERVIER (FR) 2004-04-06 US claimed
US-20030087950-A1 New alpha-amino acid sulphonyl compounds LES LABORATOIRES SERVIER (FR) 2003-05-08 US claimed
EP-0444898-A1 Cyclic hexapeptide oxytocin antagonists MERCK & CO. INC. (US) 1991-09-04 EP claimed
CN-118339274-A Brandy replica 艾娃食品实验室股份有限公司 2024-07-12 CN disclosed
CN-109879933-B Phosphoryl-containing compound and application thereof 河北科技大学 2023-06-06 CN disclosed
CN-109796519-B Steroid compound and application thereof 河北科技大学 2023-01-10 CN disclosed
CN-105705034-A Improved meat slurry methods of production and compositions 微自然有限责任公司 2016-06-22 CN disclosed
US-6716843-B2 INHIBITOR OF DIPEPTIDYL-PEPTIDASE IV LES LABORATOIRES SERVIER (FR) 2004-04-06 US disclosed
US-6716843-B2 INHIBITOR OF DIPEPTIDYL-PEPTIDASE IV LES LABORATOIRES SERVIER (FR) 2004-04-06 US disclosed
US-20040024180-A1 Process for the production of 2,5 -diketopiperazines,2,5-diketopiperazines , dipeptides and their use thereof DEGUSSA AG (DE) 2004-02-05 US disclosed
US-20030087950-A1 New alpha-amino acid sulphonyl compounds LES LABORATOIRES SERVIER (FR) 2003-05-08 US disclosed
US-20030087950-A1 New alpha-amino acid sulphonyl compounds LES LABORATOIRES SERVIER (FR) 2003-05-08 US disclosed
EP-1274693-A1 METHOD FOR PRODUCING 2,5-DIKETOPIPERAZINES, 2,5-DIKETOPIPERAZINES, DIPEPTIDES AND THE USE THEREOF Degussa AG (DE) 2003-01-15 EP disclosed
EP-1245568-A1 Sulfonyl derivatives of amino acids and their use as inhibitors of dipeptidyl-peptidase IV (DPP IV) Les Laboratoires Servier (FR) 2002-10-02 EP disclosed
WO-2001081321-A1 METHOD FOR PRODUCING 2,5-DIKETOPIPERAZINES, 2,5-DIKETOPIPERAZINES, DIPEPTIDES AND THE USE THEREOF DEGUSSA AG (DE) 2001-11-01 WO disclosed
US-4146614-A TREATMENT OF SCHIZOPHRENIA STATE OF MICHIGAN (US) 1979-03-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030087950-A1 New alpha-amino acid sulphonyl compounds DNPEP, DPP4, DPP7 DPP4 2/4885DPP8 5/4885DPP9 8/4885
US-20040024180-A1 Process for the production of 2,5 -diketopiperazines,2,5-diketopiperazines , dipeptides and their use thereof DHPS, DPP7, VIP DPP4 14/4885DPP8 73/4885DPP9 120/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.