Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 19/20 | 0.68 |
| ▸ | PLA2G10 | O15496 | 5/20 | 0.64 |
| ▸ | PLA2G2E | Q9NZK7 | 5/20 | 0.64 |
| ▸ | PLA2G1B | P04054 | 5/20 | 0.64 |
| ▸ | PLA2G5 | P39877 | 4/20 | 0.64 |
| ▸ | PLA2G2F | Q9BZM2 | 4/20 | 0.64 |
| ▸ | PLA2G2D | Q9UNK4 | 4/20 | 0.64 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.62 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.62 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.62 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.62 |
| ▸ | PLA2G3 | Q9NZ20 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8502375 | 0.90 | PLA2G2A (0.68) | PLA2G2APLA2G10PLA2G2EPLA2G1BPLA2G5 | |
| SCHEMBL8504536 | 0.90 | PLA2G2A (0.68) | PLA2G2APLA2G10PLA2G2EPLA2G1BPLA2G5 | |
| Acetic Acid Methyl Ester SCHEMBL27783716 | 0.83 | PLA2G2A (0.72) | PLA2G2APLA2G10PLA2G2EPLA2G1BPLA2G5 | |
| SCHEMBL8502450 | 0.82 | PLA2G2A (0.64) | PLA2G2APLA2G10PLA2G2EPLA2G1BPLA2G5 | |
| SCHEMBL7962736 | 0.81 | PLA2G2A (1.00) | PLA2G2APLA2G10PLA2G2EPLA2G1BPLA2G5 | |
| SCHEMBL8502374 | 0.81 | PLA2G2A (0.72) | PLA2G2APLA2G10PLA2G2EPLA2G1BPLA2G5 | |
| SCHEMBL13888556 | 0.80 | PLA2G2A (0.74) | PLA2G2APLA2G10PLA2G2EPLA2G1BPLA2G5 | |
| SCHEMBL2157520 | 0.80 | PLA2G2A (0.74) | PLA2G2APLA2G10PLA2G2EPLA2G1BPLA2G5 | |
| SCHEMBL5153390 | 0.79 | PLA2G2A (0.77) | PLA2G2APLA2G10PLA2G2EPLA2G1BPLA2G5 | |
| SCHEMBL5157365 | 0.79 | PLA2G2A (0.77) | PLA2G2APLA2G10PLA2G2EPLA2G1BPLA2G5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919810-A | SEPTIC SHOCK | ELI LILLY AND COMPANY (US) | 1999-07-06 | — | — | US | disclosed |
| US-5919943-A | INHIBITION OF SPLA2 | ELI LILLY AND COMPANY (US) | 1999-07-06 | — | — | US | disclosed |
| US-5733923-A | SECRETORY PANCREATIC PHOSPHOLIPASE A2 | ELI LILLY AND COMPANY (US) | 1998-03-31 | — | — | US | disclosed |