Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.56 |
| ▸ | IDH2 | P48735 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 4/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.53 |
| ▸ | KIF11 | P52732 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8368351 | 0.91 | RXFP1 (0.62) | MAPTMEN1KMT2AHTTRAB9A | |
| SCHEMBL5476438 | 0.84 | MEN1 (0.67) | MAPTMEN1KMT2AHTTRAB9A | |
| SCHEMBL10217915 | 0.83 | KMT2A (0.88) | MAPTMEN1KMT2AHTTRAB9A | |
| SCHEMBL28317077 | 0.82 | MEN1 (0.61) | MAPTMEN1KMT2AHTTRAB9A | |
| SCHEMBL8370337 | 0.81 | NTRK1 (0.70) | MAPTMEN1KMT2AHTTRAB9A | |
| SCHEMBL28317079 | 0.81 | IDH2 (0.70) | MAPTMEN1KMT2AHTTRAB9A | |
| SCHEMBL8370028 | 0.81 | GRIK1 (0.65) | MAPTMEN1KMT2AHTTRAB9A | |
| SCHEMBL18013182 | 0.81 | TRPV1 (0.72) | MAPTMEN1KMT2AHTTRAB9A | |
| SCHEMBL1463112 | 0.80 | KDM4E (0.71) | MAPTMEN1KMT2AHTTRAB9A | |
| SCHEMBL28151433 | 0.79 | GRIK1 (0.58) | MAPTMEN1KMT2AHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0910358-A1 | PHENYL DERIVATIVES USEFUL AS BLOCKERS OF CHLORIDE CHANNELS | NEUROSEARCH A/S (DK) | 1999-04-28 | — | — | EP | disclosed |
| WO-1997045111-A1 | PHENYL DERIVATIVES USEFUL AS BLOCKERS OF CHLORIDE CHANNELS | NEUROSEARCH A/S (DK) | 1997-12-04 | — | — | WO | disclosed |