Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | POLA1 | P09884 | 1/20 | 0.50 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3748707 | 0.81 | POLA1 (0.72) | KDM4EPOLA1 | |
| SCHEMBL25512701 | 0.81 | POLA1 (0.72) | KDM4EPOLA1 | |
| SCHEMBL3748702 | 0.81 | POLA1 (0.72) | KDM4EPOLA1 | |
| SCHEMBL11142359 | 0.79 | KDM4E (0.60) | KDM4EPOLA1P2RY1TAS1R3TAS1R1 | |
| SCHEMBL6897217 | 0.78 | POLA1 (0.70) | KDM4EPOLA1 | |
| SCHEMBL8535281 | 0.78 | POLA1 (0.70) | KDM4EPOLA1 | |
| SCHEMBL6897208 | 0.78 | POLA1 (0.70) | KDM4EPOLA1 | |
| SCHEMBL31685346 | 0.77 | KDM4E (0.59) | KDM4EPOLA1P2RY1TAS1R3TAS1R1 | |
| SCHEMBL20341115 | 0.76 | KDM4E (0.56) | KDM4EPOLA1P2RY1TAS1R3TAS1R1 | |
| SCHEMBL20341100 | 0.76 | KDM4E (0.63) | KDM4EPOLA1P2RY1TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918784-A1 | ALKYLATED NUCLEOSIDE-3'-PHOSPHATES, PROCESS FOR PRODUCING THEM AND THEIR USE | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) | 1999-06-02 | — | — | EP | disclosed |
| WO-1997043299-A1 | ALKYLATED NUCLEOSIDE-3'-PHOSPHATES, PROCESS FOR PRODUCING THEM AND THEIR USE | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) | 1997-11-20 | — | — | WO | disclosed |