Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 1/20 | 0.74 |
| ▸ | HTR2B | P41595 | 1/20 | 0.74 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 12/20 | 0.35 |
| ▸ | FEN1 | P39748 | 12/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL375979 | 0.85 | HTR1B (1.00) | HTR1BHTR2BGPR65MAPK14ALOX5AP | |
| SCHEMBL29391421 | 0.85 | HTR1B (1.00) | HTR1BHTR2BGPR65MAPK14ALOX5AP | |
| SCHEMBL29385708 | 0.85 | HTR1B (1.00) | HTR1BHTR2BGPR65MAPK14ALOX5AP | |
| SCHEMBL8469545 | 0.84 | HTR1B (0.97) | HTR1BHTR2BGPR65MAPK14ALOX5AP | |
| Hydrochloric Acid SCHEMBL5746097 | 0.84 | HTR1B (0.97) | HTR1BHTR2BGPR65MAPK14ALOX5AP | |
| SCHEMBL8331612 | 0.82 | HTR1B (0.70) | HTR1BHTR2BGPR65MAPK14ALOX5AP | |
| SCHEMBL8329611 | 0.81 | HTR1B (0.72) | HTR1BHTR2BGPR65MAPK1MAPK14 | |
| Hydrochloric Acid SCHEMBL8330244 | 0.80 | HTR1B (0.70) | HTR1BHTR2BGPR65MAPK1MAPK14 | |
| Fumaric Acid SCHEMBL5773986 | 0.79 | HTR1B (0.80) | HTR1BHTR2BGPR65ALOX5APFEN1 | |
| Maleic Acid SCHEMBL5773984 | 0.79 | HTR1B (0.80) | HTR1BHTR2BGPR65ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958934-A | 5-HT 2B ANTAGONIST | SYNTEX (U.S.A.) INC. (US) | 1999-09-28 | — | — | US | disclosed |