Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 11/20 | 0.54 |
| ▸ | HTR1B | P28222 | 10/20 | 0.54 |
| ▸ | MPO | P05164 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8507874 | 0.81 | HTR1D (0.80) | HTR1DHTR1BMPOHTR2A | |
| SCHEMBL8507140 | 0.81 | HTR1D (0.58) | HTR1DHTR1BMPOHTR2AHTR1A | |
| SCHEMBL22643882 | 0.78 | HTR1D (0.58) | HTR1DHTR1BMPOHTR2AHTR1A | |
| SCHEMBL8506245 | 0.75 | HTR1D (0.37) | HTR1DHTR1BHTR2A | |
| SCHEMBL8507362 | 0.70 | HTR1D (1.00) | HTR1DHTR1BMPOHTR2A | |
| SCHEMBL8506246 | 0.69 | SLC6A4 (0.62) | HTR1DHTR1B | |
| SCHEMBL10574079 | 0.69 | HTR2A (0.62) | HTR1DHTR1BMPOHTR2AHTR1A | |
| SCHEMBL20077509 | 0.68 | HTR1D (0.44) | HTR1DHTR1BHTR2A | |
| SCHEMBL23030468 | 0.67 | HTR1D (0.43) | HTR1DHTR1BHTR2A | |
| SCHEMBL22643951 | 0.67 | HTR1D (0.75) | HTR1DHTR1BMPOHTR2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998462-A | SEROTONIN RECEPTOR ANTAGONIST | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1999-12-07 | — | — | US | disclosed |
| WO-1998027089-A1 | 5-ALKYL INDOLE COMPOUNDS AS 5-HT1D-LIKE LIGANDS | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1998-06-25 | — | — | WO | disclosed |