Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 10/20 | 0.80 |
| ▸ | HTR1B | P28222 | 9/20 | 0.80 |
| ▸ | MPO | P05164 | 3/20 | 0.62 |
| ▸ | HTR2A | P28223 | 3/20 | 0.60 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8507362 | 0.89 | HTR1D (1.00) | HTR1DHTR1BMPOHTR2ABRD4 | |
| SCHEMBL22643882 | 0.82 | HTR1D (0.58) | HTR1DHTR1BMPOHTR2A | |
| SCHEMBL8506249 | 0.81 | HTR1D (0.54) | HTR1DHTR1BMPOHTR2A | |
| SCHEMBL27531605 | 0.81 | HTR1D (0.68) | HTR1DHTR1BMPOHTR2ABRD4 | |
| SCHEMBL8506288 | 0.80 | HTR1D (1.00) | HTR1DHTR1BMPOHTR2ABRD4 | |
| SCHEMBL8506914 | 0.79 | HTR1D (0.71) | HTR1DHTR1BMPOHTR2ABRD4 | |
| SCHEMBL8506246 | 0.77 | SLC6A4 (0.62) | HTR1DHTR1BHTR6 | |
| SCHEMBL2933511 | 0.77 | HTR1A (0.75) | HTR1DHTR1BMPOHTR2A | |
| SCHEMBL27095364 | 0.77 | HTR7 (0.71) | HTR1DHTR1BMPOHTR2AHTR6 | |
| SCHEMBL733997 | 0.77 | MPO (1.00) | HTR1DHTR1BMPOHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998462-A | SEROTONIN RECEPTOR ANTAGONIST | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1999-12-07 | — | — | US | disclosed |