Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 12/20 | 0.44 |
| ▸ | CNR1 | P21554 | 4/20 | 0.41 |
| ▸ | RORA | P35398 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | RORB | Q92753 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8506254 | 0.84 | CNR2 (0.42) | CNR2CNR1RORARORCRORB | |
| SCHEMBL4856635 | 0.79 | CNR2 (0.49) | CNR2CNR1SLC6A3TLR8 | |
| SCHEMBL14051803 | 0.73 | PTGS2 (0.51) | CNR2CNR1ALDH1A1SLC6A3 | |
| SCHEMBL21501948 | 0.69 | KDM4E (0.49) | CNR2CNR1RORARORCRORB | |
| SCHEMBL8505497 | 0.69 | KDM4E (0.55) | CNR2CNR1ALDH1A1TLR8 | |
| SCHEMBL30641152 | 0.67 | CNR2 (0.42) | CNR2CNR1ALDH1A1SLC6A3 | |
| Decane SCHEMBL9931523 | 0.67 | CNR1 (0.51) | CNR2CNR1ALDH1A1TLR8 | |
| Tetradecane SCHEMBL9931525 | 0.67 | CNR1 (0.51) | CNR2CNR1ALDH1A1TLR8 | |
| SCHEMBL30641161 | 0.65 | TLR8 (0.55) | CNR2CNR1TLR8 | |
| SCHEMBL31498033 | 0.65 | CNR2 (0.59) | CNR2CNR1ALDH1A1SLC6A3TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5986106-A | Process for preparing 4-substituted-1H-indole-3-glyoxamides | ELI LILLY AND COMPANY (US) | 1999-11-16 | — | — | US | disclosed |
| WO-1999000360-A1 | PROCESS FOR PREPARING 4-SUBSTITUTED-1H-INDOLE-3-GLYOXAMIDES | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | WO | disclosed |
| EP-0887342-A2 | Process for preparing 4-substituted-1H-indole-3-glyoxamides | ELI LILLY AND COMPANY (US) | 1998-12-30 | — | — | EP | disclosed |